| Entry date | September 27, 2002  07:28 +1GMT
  |  | Last update | June 10, 2022  16:38 +1GMT
  |  
| Allergome Code | 694
  |  
| Name | Ana c 2  
  |  
| Common Names | a3077, a694, Ananain, Bromelain, CCD-bearing Protein (XF), Cysteine Protease, Food, k202
  |  
| Biological Function | Proteases
  |  
Isoforms, Variants, Epitopes | Ana c 2.0101, Ana c 2.0101 (MUXF3)
  |  
Links to Molecule Sequences | Ana c 2 - F1KD58 - UNIPROT, Ana c 2 - F8UN02 - UNIPROT, Ana c 2 - L7UXZ2 - UNIPROT, Ana c 2 - O23799 - UNIPROT, Ana c 2 - O23800 - UNIPROT, Ana c 2 - O23801 - UNIPROT, Ana c 2 - O24641 - UNIPROT, Ana c 2 - O81084 - UNIPROT, Ana c 2 - O81085 - UNIPROT, Ana c 2 - P80884 - UNIPROT, Ana c 2 - Q7DNA3 - UNIPROT, Ana c 2 - S5VRY7 - UNIPROT, Ana c 2 - Wiki, Ana c 2.0101 - O23791 - UNIPROT
  |  
| Sources |  |  
Links to Source Taxonomy | Ana c - 42335 - ITIS, Ana c - 4615 - NCBI, Ana c - 4615 - UniProt, Ana c - Discover Life, Ana c - Wikipedia
  |  
| Links to Source Images | Ananas comosus on Google images |  | Tissues | Fruit, Stem
  |  
| Routes of Exposure | Ingestion, Inhalation
  |  
Epidemiology from Literature | | Cohort | Year | Country | Test | Subjects | Positive (%) | Bibliography |  | 1.10 - Any allergy symptom, Diagnosed | 2010 | Italy | IgE | 16,408 | 2.450 | 20100301, Scala E
	 |  | 1.4 - Respiratory Symptoms, Diagnosed | 2002 | Italy | IgE | 1,831 | 23.000 | 2002, Mari A
	 |  | 1.10 - Any allergy symptom, Diagnosed | 2011 | Spain | IgE | 1,018 | 13.550 | 20111011, Vidal C
	 |  | 4.1.3 - Heterologous Source Sensitized (SPT) | 2001 | Italy | SPT | 548 | 43.900 | 2001, Mari A
	 |  | 6.2 - General Population (Adults) | 2012 | Sweden | IgE | 371 | 0.000 | 20120528, Patelis A
	 |  | 4.1.3 - Heterologous Source Sensitized (SPT) | 1999 | Italy | IgE | 326 | 41.700 | 1999, Mari A
	 |  | 1.8 - Fruit Allergy | 2012 | Spain | IgE | 212 | 10.000 | 20120912, Palacin A
	 |  | 4.1.5 - Heterologous Source Sensitized (IgE) | 2010 | Sweden | IgE | 150 | 8.660 | 20100212, Asarnoj A
	 |  | 1.5 - Atopic Dermatitis, Diagnosed | 2013 | Germany | IgE | 140 | 5.000 | 20130111, Ott H
	 |  | 4.1.7 - Heterologous Source Sensitized (Symptoms, SPT, IgE) | 2014 | Spain | IgE | 130 | 33.800 | 20140401, Armentia A
	 |  | 1.9 - Pollen Allergy | 2012 | Spain | IgE | 117 | 5.000 | 20120912, Palacin A
	 |  | 1.3 - Rhinitis, Diagnosed | 2013 | Brazil | IgE | 101 | 1.900 | 20130912, Lacerda Araujo LM
	 |  | 4.1.2 - Heterologous Source Sensitized (Symptoms, SPT) | 2011 | China | IgE | 100 | 0.000 | 20111214, Zheng YW
	 |  | 4.1.7 - Heterologous Source Sensitized (Symptoms, SPT, IgE) | 2008 | Switzerland | IgE | 99 | 29.290 | 20081218, Muller UR
	 |  | 4.1.7 - Heterologous Source Sensitized (Symptoms, SPT, IgE) | 2008 | Switzerland | IgE | 99 | 12.120 | 20081218, Muller UR
	 |  | 5.3.1 - Source Exposed (Symptoms, IgE) | 2012 | Belgium | IgE | 99 | 4.040 | 20110223, De Knop KJ
	 |  | 4.1.7 - Heterologous Source Sensitized (Symptoms, SPT, IgE) | 2012 | France | IgE | 97 | 7.210 | 20120706, Garnier L
	 |  | 1.2.1 - Asthma, Diagnosed (Adults) | 2012 | Sweden | IgE | 96 | 1.040 | 20120528, Patelis A
	 |  | 1.10 - Any allergy symptom, Diagnosed | 2010 | Belgium | IgE | 86 | 12.790 | 20101214, Gadisseur R
	 |  | 4.1.8 - Heterologous Source Sensitized (SPT, IgE) | 2012 | Spain | IgE | 68 | 0.000 | 20120726, Pedrosa M
	 |  | ... complete "Epidemiology from Literature" listing -> |  
  |  | References | Biochemistry / Structure / Function 2013: 20130429, Foster ES
	 2012: 20120912, Palacin A
	 - 20120807, Young GJ
	 - 20120720, Santiago HC
	 - 20120405, Al-Ghouleh A
	 2011: 20111107, Pfiffner P
	 - 20110411, Kaulfuerst-Soboll H
	 2007: 20070913, Nieuwenhuizen NJ
	 2006: 20060620, Gupta P
	 2002: 2002, Fu TJ
	 2000: 2000a, van Ree R
	 - 20000412, Choi KH
	 - 2000, Hiemori M
	 1999: 1999, Zeleny R
	 - 1999, Mari A
	 1998: 1998, Wilson IB
	 1996: 1996, Garcia-Casado G
	 - 1996, Cambra O
	 1993: 1993, Tretter V
	 1991: 1991, Tretter V
	 ... complete Reference listing ->
  Immunochemistry / Allergenicity 2014: 20141003, Beitia JM
	 - 20140916, Richard C
	 - 20140214, Rodriguez-Perez R
	 - 20140210, Aberer W
	 2013: 20131220, Castro L
	 - 20130927, Holzweber F
	 - 20130614, Amoah AS
	 - 20130420, Palazzo P
	 - 20130125, Aranda A
	 2012: 20121228, Palacin A
	 - 20120912, Palacin A
	 - 20120425, Pasquariello MS
	 2011: 20111112, Kasera R
	 - 20110411, Kaulfuerst-Soboll H
	 - 20110401, Mertens M
	 2010: 20100722, Fremont S
	 - 20100706, Hino S
	 - 20100514, Mittermann I
	 2009: 20090420, Seppala U
	 2008: 20080802, Palacin A
	 ... complete Reference listing ->
  Immune-mechanisms / Genetics 2012: 20120405, Al-Ghouleh A
	 2009: 20090126, Secor ER Jr
	
  Epidemiology 2013: 20130912, Lacerda Araujo LM
	 - 20130614, Amoah AS
	 - 20130420, Palazzo P
	 2012: 20121228, Palacin A
	 - 20120912, Palacin A
	 - 20120528, Patelis A
	 - 20120224, Rossi RE
	 2011: 20111214, Zheng YW
	 - 20111011, Vidal C
	 2010: 20100301, Scala E
	 2009: 20090826, Ebo DG
	 2007: 20070919, Raulf-Heimsoth M
	 2006: 20060512, Reuter A
	 2003: 2003, Mari A
	 2002: 2002, Mari A
	 2001: 2001a, Rossi RE
	 - 2001, Mari A
	 1999: 1999, Mari A
	
  Diagnosis 2014: 20141114, Lambert C
	 - 20140921, Ward BJ
	 - 20140916, Richard C
	 - 20140718, Faber MA
	 - 20140609, Rentzos G
	 - 20140417, Micucci C
	 - 20140401, Armentia A
	 - 20140331, Rockmann H
	 - 20140324, Heaps A
	 - 20140210, Aberer W
	 2013: 20131209, Cabauatan CR
	 - 20131206, Seyfarth F
	 - 20131028, Lupinek C
	 - 20130927, Holzweber F
	 - 20130927, Borghesan F
	 - 20130819, Bansal AS
	 - 20130729, Passalacqua G
	 - 20130401, Roncati L
	 - 20130318, Foetisch K
	 - 20130204, De Swert L
	 ... complete Reference listing ->
  Experimental Model - Allergic Immune Response 2014: 20140325, Hara K
	 - 20140101, Secor ER Jr
	 2012: 20120404, Cunningham PT
	 2007: 20071224, Sokol CL
	 2006: 20060628, Suzuki M
	 2005: 20051223, Jin C
	
  Experimental Model - Inhalant-induced Diseases 2014: 20140325, Hara K
	 2012: 20120404, Cunningham PT
	 2006: 20060628, Suzuki M
	
  Review, Editorial, Report Citations, Other Resources 2014: 20141128, Commins SP
	 - 20140919, Unsworth DJ
	 - 20140911, Sun-Waterhouse D
	 - 20140821, Arshad ZI
	 2013: 20131004, Canonica GW
	 - 20130807, Douladiris N
	 - 20130529, Baur X
	 - 20130420, Molassiotis A
	 - 20130323, Ciardiello MA
	 2012: 20121018, Treudler R
	 - 20120111, Treudler R
	 2011: 20110629, Porter PC
	 - 20110627, Macchia D
	 - 20110212, Moneret-Vautrin DA
	 2010: 20101206, Herman EM
	 - 20101022, Rueff F
	 - 20100610, Quirce S
	 - 20100604, De Knop KJ
	 2009: 20091224, Commins S
	 - 20091009, Commins SP
	 ... complete Reference listing -> |  
  |